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Organoid Medicine Milestone Reported in Cell Stem Cell

Organoid Medicine Milestone Reported in Cell Stem Cell

Lab-grown human tissue successfully repairs damaged intestines in rodent model. Achievement led by experts at Cincinnati Children’s moves years-long research effort closer to first-in-human clinical trial. Potential benefits include new therapies for ulcerative colitis, Crohn’s disease, and more.

CINCINNATI, Sept. 12, 2024 /PRNewswire/ — In this science story, there has not been just one, big “Eureka!” moment, there have been a chain of them dating back more than 15 years.

One such moment arrived in 2019 when Holly Poling, a staff investigator at Cincinnati Children’s, saw microscopic proof that organoids—once the stuff of theory, of distant possibility—actually restored function to a small loop of severely damaged intestine.